11 Apr 2018 ... IntEREst is an R package for Intron retention and exon-exon junction ... application of IntEREst is not limited to the comparison of these intron types. ... This results in a more symmetric distribution of up/down regulated intron retention signals (Fig ... Braunschweig U, Barbosa-Morais NL, Pan Q, Nachman EN, ...
8 Apr 2017 ... However, the “non-productive” label should not be taken to imply lack ... Intron retention is most often associated with down-regulation of gene ...
14 Nov 2019 ... The fate of an intron to be, or not to be, retained in the mature transcript ... of genes with neuron-specific functions and down-regulation of genes ...
Moreover, retained introns that are predicted not to introduce an NMD-eliciting ... to down-regulate transcripts from genes, the expression of which is either not ...
16 Nov 2017 ... Intron-retaining genes have significantly longer 3′ UTR sequences, with a ... We argue therefore in zebrafish that IR is not as important ... Braunschweig U, Barbosa-Morais NL, Pan Q, Nachman EN, Alipanahi ... is accompanied by up-regulation of p27kip1 and down-regulation of CDK2, CDK4, and CDK6.
GVL logo · Melbourne Bioinformatics logo ... If not, switch to it. ... Click on the Workflows link in the top menu; Click on the down arrow on your workflow's button.
We have also interest on biomedicine, namely on how the genomic findings can be used to provide a deeper knowledge and a better treatment for human ...
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The LH receptor (LHR) mediates the actions of LH and human chorionic gonadotropin (hCG). In vivo data showed that deletion of exon 10 does not affect hCG action. ... 1 May 2003, Pages 2242–2249, https://doi.org/10.1210/jc.2002-021946 ... or too short to turn the bound LH molecule down to the transmembrane domain.
While introns do not encode protein products, they are integral to gene expression regulation. Some introns themselves encode functional RNAs through further ...
20 Mar 2019 ... Atlas-CNV is validated as a method to identify exonic CNVs in targeted ... In these methods, however, each single-exon CNV is treated equally and there is no mechanism to evaluate the ... Values in bars represent the sample count broken down by CNV type ... Johansson LF, van Dijk F, de Boer EN, et al.
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Source: http://tanglab.hebtu.edu.cn/tanglab/down load/DREAMSeq/1.0.4/DREAMSeq_1.0.4.zip; Documentation: http://tanglab.hebtu.edu.cn/tanglab/down
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These chromosomes are further broken down into smaller pieces of code called Genes. The 23 pairs of chromosomes consist of about 70,000 genes and every ...
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